BDBM50211362 5-methyl-1H-pyrazole-3-carboxylic acid::5-methyl-3-carboxyl-pyrazole::5-methylpyrazole-3-carboxylic acid::CHEMBL391574
SMILES Cc1cc(n[nH]1)C(O)=O
InChI Key InChIKey=WSMQKESQZFQMFW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50211362
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 933nMAssay Description:Inhibition of porcine kidney DAAO using D-serine as substrate by Amplex red and horseradish peroxidase fluorescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 460nMAssay Description:Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production testMore data for this Ligand-Target Pair
Affinity DataIC50: 473nMAssay Description:Inhibition of human recombinant DAAO expressed in Escherichia coli assessed as H2O2 production from D-serine degradation after 30 mins by fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Inhibition of human DAAOMore data for this Ligand-Target Pair
Affinity DataKd: 617nMAssay Description:Binding affinity to human recombinant DAAO by isothermal titration calorimeter analysisMore data for this Ligand-Target Pair
Affinity DataKd: 900nMAssay Description:Binding affinity to human recombinant DAAO by kinetic study scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of bovine recombinant DASPO expressed in Escherichia coli preincubated for 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by whole cell voltage patch clamp techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 4.34E+5nMAssay Description:Agonist activity at GPR109A receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced intracellular cAMP production by Flashplate...More data for this Ligand-Target Pair
Affinity DataEC50: 900nMAssay Description:Activation of GPR109A receptor in CHOK1 cells assessed as ERK1/2 MAP kinase activation by ELISAMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
"Sapienza" Universit£
Curated by ChEMBL
"Sapienza" Universit£
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of RNase H activity of recombinant His-tagged HIV-1 group M subtype B reverse transcriptase p66/p51 expressed in Escherichia coli M15 usin...More data for this Ligand-Target Pair
Affinity DataIC50: 933nMAssay Description:Inhibition of porcine kidney DAAO using D-serine as substrate assessed as H2O2 formation by amplex red and peroxidase-coupled continuous fluorescence...More data for this Ligand-Target Pair
Affinity DataIC50: 910nMAssay Description:Inhibition of human D-amino acid oxidaseMore data for this Ligand-Target Pair