BDBM50212927 (1S,2R,5S)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-2-(2,4,5-trifluorophenyl)cyclohexanamine::(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE::CHEMBL233360::CHEMBL233360 (15)

SMILES N[C@H]1C[C@H](CC[C@@H]1c1cc(F)c(F)cc1F)N1CCn2c(C1)nnc2C(F)(F)F

InChI Key InChIKey=CNKRZILQBKJWDS-WMFXKJRFSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50212927   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM50212927((1S,2R,5S)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2...)
Affinity DataIC50:  21nMAssay Description:The HypoGen module in DS2.5 was employed to produce pharmaphores with the training set compounds.More data for this Ligand-Target Pair
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212927((1S,2R,5S)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212927((1S,2R,5S)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM50212927((1S,2R,5S)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2...)
Affinity DataIC50:  21nMAssay Description:Inhibition of dipeptidyl peptidase 4 (unknown origin)More data for this Ligand-Target Pair
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212927((1S,2R,5S)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212927((1S,2R,5S)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
China Pharmaceutical University

LigandPNGBDBM50212927((1S,2R,5S)-5-(3-(trifluoromethyl)-5,6-dihydro-[1,2...)
Affinity DataIC50:  21nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair