BDBM50213119 (R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-benzenediol::CHEMBL229620::US10617654, Compound (R)-7::US10925840, Compound (R)-7::US9492405, (R)-7::US9492405, 25

SMILES O[C@@H](CNCCc1ccccc1)c1cc(O)cc(O)c1

InChI Key InChIKey=IQFFDUZWXIAVOU-INIZCTEOSA-N

Data  8 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50213119   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM50213119((R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKi:  1.05E+4nM ΔG°:  -6.31kcal/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM50213119((R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKi:  1.05E+4nMAssay Description:Displacement of [3H]CGP12177 from human beta-2 adrenergic receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM50213119((R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKi:  4.25E+4nM ΔG°:  -5.54kcal/molepH: 7.8 T: 2°CAssay Description:Beta1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988)....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-1 adrenergic receptor(Rattus norvegicus (Rat))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM50213119((R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKi:  4.25E+4nMAssay Description:Displacement of [3H]CGP-12177 from beta-1 adrenergic receptor in Sprague-Dawley rat cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM50213119((R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKi:  1.05E+7nMAssay Description:Twenty-four hours after adenoviral infection with human β2-AR, HEK293 cells were harvested in lysis buffer, Tris-HCl [5 mM, pH 7.4] containing E...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM50213119((R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKi:  1.05E+7nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-1 adrenergic receptor(Mus musculus)
The Usa, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM50213119((R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKi:  4.25E+7nMAssay Description:β1-AR binding was done on rat cortical membrane following a previously described procedure (Beer et al., Biochem. Pharmacol. 37: 1145-1151, 1988...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
The Usa, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM50213119((R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKi:  4.25E+7nMAssay Description:Twenty-four hours after adenoviral infection with human β2-AR, HEK293 cells were harvested in lysis buffer, Tris-HCl [5 mM, pH 7.4] containing E...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM50213119((R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKd:  1.05E+4nMAssay Description:HEK 293 cells stability transfected with cDNA encoding human β2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

US Patent
LigandPNGBDBM50213119((R)-(-)-5-(1-hydroxy-2-phenethylaminoethyl)-1,3-be...)
Affinity DataKd:  1.05E+4nMpH: 7.7Assay Description:HEK 293 cells stability transfected with cDNA encoding human beta2-AR (provided by Dr. Brian Kobilka, Stanford Medical Center, Palo Alto, Calif.) wer...More data for this Ligand-Target Pair
In DepthDetails US Patent