BDBM50214606 4'-chloro-biphenyl-4-carboxylic acid (2-imidazol-1-yl-2-phenyl-ethyl)-amide::Azole, 12::CHEMBL253613

SMILES Clc1ccc(cc1)-c1ccc(cc1)C(=O)NCC(c1ccccc1)n1ccnc1

InChI Key InChIKey=FHHNSSGZEIVGMS-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50214606   

TargetLanosterol 14-alpha-demethylase(Trypanosoma brucei)
Vanderbilt University

LigandPNGBDBM50214606(4'-chloro-biphenyl-4-carboxylic acid (2-imidazol-1...)
Affinity DataKd:  40nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50214606(4'-chloro-biphenyl-4-carboxylic acid (2-imidazol-1...)
Affinity DataIC50:  15nMAssay Description:Inhibition of CYP24 in human keratinocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Homo sapiens (Human))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50214606(4'-chloro-biphenyl-4-carboxylic acid (2-imidazol-1...)
Affinity DataIC50:  616nMAssay Description:Inhibition of CYP27B1 in human keratinocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi)
Vanderbilt University

LigandPNGBDBM50214606(4'-chloro-biphenyl-4-carboxylic acid (2-imidazol-1...)
Affinity DataKd:  70nMpH: 6.0Assay Description:Azole derivatives used as an inhibitor of TB and TC CYP51.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed