BDBM50222287 6,7-dihydroxy-4'-methoxyisoflavone::CHEMBL239028::IR-2::formonetin
SMILES COc1ccc(cc1)-c1coc2cc(O)c(O)cc2c1=O
InChI Key InChIKey=GCWOYVFHJDNKIN-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50222287
Affinity DataIC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+5nMpH: 8.0Assay Description:Approximately 2 µg of either COX-1 or COX-2 was added to buffer containing 100 µM AA, 0.1 M Tris-HCl buffer (pH 8.0), 5 mM EDTA, 2 mM phenol, and 1 µ...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile
Curated by ChEMBL
Universidad De Santiago De Chile
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 15-hLO2More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile
Curated by ChEMBL
Universidad De Santiago De Chile
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+5nMpH: 8.0Assay Description:Approximately 2 µg of either COX-1 or COX-2 was added to buffer containing 100 µM AA, 0.1 M Tris-HCl buffer (pH 8.0), 5 mM EDTA, 2 mM phenol, and 1 µ...More data for this Ligand-Target Pair