BDBM50222297 7,8-dihydroxy-4'-methylisoflavone::CHEMBL395449::IR-303

SMILES Cc1ccc(cc1)-c1coc2c(O)c(O)ccc2c1=O

InChI Key InChIKey=OANWEBOHKLZIJJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50222297   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM50222297(7,8-dihydroxy-4'-methylisoflavone | CHEMBL395449 |...)
Affinity DataIC50: >1.00E+5nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM50222297(7,8-dihydroxy-4'-methylisoflavone | CHEMBL395449 |...)
Affinity DataIC50:  250nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222297(7,8-dihydroxy-4'-methylisoflavone | CHEMBL395449 |...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

Curated by ChEMBL
LigandPNGBDBM50222297(7,8-dihydroxy-4'-methylisoflavone | CHEMBL395449 |...)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM50222297(7,8-dihydroxy-4'-methylisoflavone | CHEMBL395449 |...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 15-hLO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed