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BDBM50223675 CHEMBL251369::N-(2-morpholinophenyl)-5-nitrofuran-2-carboxamide::cid_2996093

SMILES: [O-][N+](=O)c1ccc(o1)C(=O)Nc1ccccc1N1CCOCC1

InChI Key: InChIKey=BIQWNNXDPVEAPZ-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50223675   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vma11p


(Saccharomyces cerevisiae S288c)
BDBM50223675
PNG
(CHEMBL251369 | N-(2-morpholinophenyl)-5-nitrofuran...)
Show SMILES [O-][N+](=O)c1ccc(o1)C(=O)Nc1ccccc1N1CCOCC1
Show InChI InChI=1S/C15H15N3O5/c19-15(13-5-6-14(23-13)18(20)21)16-11-3-1-2-4-12(11)17-7-9-22-10-8-17/h1-6H,7-10H2,(H,16,19)
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

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Article
PCBioAssay
n/an/an/an/a 2.53E+4n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1 R03 DA031666-01A1 Project Title: Flow Cytometry HTS of Small Molecules that Regulate V-ATPa...


PubChem Bioassay (2012)


Article DOI: 10.1016/j.bioorg.2016.08.005
BindingDB Entry DOI: 10.7270/Q2MK6BGR
More data for this
Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor


(Homo sapiens (Human))
BDBM50223675
PNG
(CHEMBL251369 | N-(2-morpholinophenyl)-5-nitrofuran...)
Show SMILES [O-][N+](=O)c1ccc(o1)C(=O)Nc1ccccc1N1CCOCC1
Show InChI InChI=1S/C15H15N3O5/c19-15(13-5-6-14(23-13)18(20)21)16-11-3-1-2-4-12(11)17-7-9-22-10-8-17/h1-6H,7-10H2,(H,16,19)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/a 1.10E+3n/an/an/an/an/an/a



Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinase


Bioorg Med Chem Lett 17: 6070-4 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.057
BindingDB Entry DOI: 10.7270/Q2028R9G
More data for this
Ligand-Target Pair
Vma11p


(Saccharomyces cerevisiae S288c)
BDBM50223675
PNG
(CHEMBL251369 | N-(2-morpholinophenyl)-5-nitrofuran...)
Show SMILES [O-][N+](=O)c1ccc(o1)C(=O)Nc1ccccc1N1CCOCC1
Show InChI InChI=1S/C15H15N3O5/c19-15(13-5-6-14(23-13)18(20)21)16-11-3-1-2-4-12(11)17-7-9-22-10-8-17/h1-6H,7-10H2,(H,16,19)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PCBioAssay
n/an/an/an/a 4.18E+3n/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: 1 R03 DA031666-01A1 Project Title: Flow Cytometry HTS of Small Molecules that Regulate V-ATPa...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q23N220P
More data for this
Ligand-Target Pair