BDBM50226437 2-AMINO-6-(2-PHENYLETHYL)PYRIMIDIN-4(3H)-ONE::2-amino-6-phenethyl-3H-pyrimidin-4-one::2-amino-6-phenethylpyrimidin-4(3H)-one::CHEMBL235821

SMILES Nc1nc(CCc2ccccc2)cc(=O)[nH]1

InChI Key InChIKey=CNBSPUGFNQVSJS-UHFFFAOYSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226437   

TargetEndothiapepsin(Cryphonectria parasitica)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50226437(2-AMINO-6-(2-PHENYLETHYL)PYRIMIDIN-4(3H)-ONE | 2-a...)
Affinity DataKd:  2.20E+5nMAssay Description:Binding affinity to endothiapepsin by Biocore ISAMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50226437(2-AMINO-6-(2-PHENYLETHYL)PYRIMIDIN-4(3H)-ONE | 2-a...)
Affinity DataKd:  6.60E+5nMAssay Description:Binding affinity to BACE1 expressed in HEK293 cells by Biocore ISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed