BDBM50227151 2-(5-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl)benzylamino)naphthalen-1-yl)acetic acid::CHEMBL253311

SMILES OC(=O)Cc1cccc2c(NCc3cccc(c3)-c3c(Cc4ccccc4)cnc4c(cccc34)C(F)(F)F)cccc12

InChI Key InChIKey=FMNHPFYLVZKAJK-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50227151   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227151(2-(5-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataEC50:  355nMAssay Description:Agonist activity at human LXRbeta expressed in Huh7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227151(2-(5-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataIC50:  5nMAssay Description:Binding affinity at human LXRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227151(2-(5-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataEC50:  685nMAssay Description:Agonist activity at human LXRalpha expressed in Huh7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227151(2-(5-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataEC50:  84nMAssay Description:Agonist activity at human recombinant PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50227151(2-(5-(3-(3-benzyl-8-(trifluoromethyl)quinolin-4-yl...)
Affinity DataIC50:  123nMAssay Description:Binding affinity at human LXRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed