BDBM50227765 3-(4-(3-((5-chloro-3-methyl-1H-indole-2-carboxamido)methyl)phenoxy)-2-methylphenyl)propanoic acid::CHEMBL235143

SMILES Cc1c([nH]c2ccc(Cl)cc12)C(=O)NCc1cccc(Oc2ccc(CCC(O)=O)c(C)c2)c1

InChI Key InChIKey=RNGBTTOZWKPKDI-UHFFFAOYSA-N

Data  6 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50227765   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227765(3-(4-(3-((5-chloro-3-methyl-1H-indole-2-carboxamid...)
Affinity DataIC50:  2.10E+3nMAssay Description:Displacement of [3H]-2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227765(3-(4-(3-((5-chloro-3-methyl-1H-indole-2-carboxamid...)
Affinity DataEC50:  6nMAssay Description:Agonist activity at human PPARdelta expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227765(3-(4-(3-((5-chloro-3-methyl-1H-indole-2-carboxamid...)
Affinity DataIC50:  27nMAssay Description:Displacement of [3H]-2-methyl-2-(4-{3-{propyl-(5-pyridin-2-yl-thiophene-2-sulfonyl)-amino}-propyl}-phenoxy)-propionic acid from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227765(3-(4-(3-((5-chloro-3-methyl-1H-indole-2-carboxamid...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]-2-(4-{2-[3-(2,4-difluoro-phenyl)-1-heptyl-ureido]-ethyl}-phenoxy)-2-methyl-butyric acid from human PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227765(3-(4-(3-((5-chloro-3-methyl-1H-indole-2-carboxamid...)
Affinity DataIC50:  27.0nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227765(3-(4-(3-((5-chloro-3-methyl-1H-indole-2-carboxamid...)
Affinity DataEC50:  558nMAssay Description:Agonist activity at human PPARalpha expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227765(3-(4-(3-((5-chloro-3-methyl-1H-indole-2-carboxamid...)
Affinity DataIC50:  2.10E+3nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227765(3-(4-(3-((5-chloro-3-methyl-1H-indole-2-carboxamid...)
Affinity DataIC50:  3nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50227765(3-(4-(3-((5-chloro-3-methyl-1H-indole-2-carboxamid...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human PPARgamma expressed in CV1 cells by receptor transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed