BDBM50228440 5-chloro-2-(2-((dimethylamino)methyl)-4-(2-fluoroethoxy)phenylthio)benzenamine::CHEMBL239079

SMILES CN(C)Cc1cc(OCCF)ccc1Sc1ccc(Cl)cc1N

InChI Key InChIKey=VGVAYDIHTPWEKS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50228440   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228440(5-chloro-2-(2-((dimethylamino)methyl)-4-(2-fluoroe...)
Affinity DataKi:  0.0300nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228440(5-chloro-2-(2-((dimethylamino)methyl)-4-(2-fluoroe...)
Affinity DataKi:  97nMAssay Description:Displacement of [125I]-iodonisoxetine from NET expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228440(5-chloro-2-(2-((dimethylamino)methyl)-4-(2-fluoroe...)
Affinity DataKi:  847nMAssay Description:Displacement of [125I]N-(3'-iodopropen-2'yl)-2-beta-carbomethoxy-3-beta-(4-chlorophenyl)tropane from DAT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed