BDBM50231481 3-bromo-N-(4-(1-(2-guanidino-2-oxoethyl)-5-phenyl-1H-pyrrol-2-yl)phenyl)benzamide::3-bromo-N-[4-[1-(2-carbamimidamido-2-oxo-ethyl)-5-phenyl-pyrrol-2-yl]phenyl]benzamide::3-bromo-N-{4-[1-(2-guanidino-2-oxo-ethyl)-5-phenyl-1H-pyrrol-2-yl]-phenyl}-benzamide::CHEMBL252189

SMILES NC(=N)NC(=O)Cn1c(ccc1-c1ccc(NC(=O)c2cccc(Br)c2)cc1)-c1ccccc1

InChI Key InChIKey=XWWAMKGNSKOVNS-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50231481   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50231481(3-bromo-N-(4-(1-(2-guanidino-2-oxoethyl)-5-phenyl-...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of BACE1 assessed as reduction of total cellular amyloid beta formation by ELISAMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50231481(3-bromo-N-(4-(1-(2-guanidino-2-oxoethyl)-5-phenyl-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50231481(3-bromo-N-(4-(1-(2-guanidino-2-oxoethyl)-5-phenyl-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50231481(3-bromo-N-(4-(1-(2-guanidino-2-oxoethyl)-5-phenyl-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50231481(3-bromo-N-(4-(1-(2-guanidino-2-oxoethyl)-5-phenyl-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair