BDBM50232007 GANOMYCIN B

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](=[#6]\[#6]-c1cc(-[#8])ccc1-[#8])-[#6](-[#8])=O

InChI Key InChIKey=HVLZHPCKWVKAQH-IRQOBONWSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50232007   

TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50232007(GANOMYCIN B)
Affinity DataKi:  4.00E+3nMAssay Description:Competitive inhibition of HIV1 protease by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50232007(GANOMYCIN B)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of recombinant HIV1 protease after 30 mins by reverse phase HPLCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Sus scrofa)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50232007(GANOMYCIN B)
Affinity DataIC50:  2.93E+4nMAssay Description:Inhibition of HMG-CoA reductase in pig liver microsomes using HMG-CoA as substrate preincubated for 5 mins followed by NADPH addition measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50232007(GANOMYCIN B)
Affinity DataIC50:  3.55E+4nMAssay Description:Inhibition of sucrase in rat small intestinal mucosa assessed as reduction in glucose production using sucrose as substrate measured after 40 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed