BDBM50232524 (2R)-4-[8,8-dimethyl-3-(trifluoromethyl)-5,6-dihydro[[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-oxo-1-(2,4,5-trifluorophenyl)butan-2-amine hydrochloride::CHEMBL536088

SMILES CC1(C)N(CCn2c(nnc12)C(F)(F)F)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=LUMJCBDYZFHCSE-SNVBAGLBSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50232524   

TargetXaa-Pro dipeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232524((2R)-4-[8,8-dimethyl-3-(trifluoromethyl)-5,6-dihyd...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232524((2R)-4-[8,8-dimethyl-3-(trifluoromethyl)-5,6-dihyd...)
Affinity DataIC50:  175nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232524((2R)-4-[8,8-dimethyl-3-(trifluoromethyl)-5,6-dihyd...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232524((2R)-4-[8,8-dimethyl-3-(trifluoromethyl)-5,6-dihyd...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXaa-Pro aminopeptidase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232524((2R)-4-[8,8-dimethyl-3-(trifluoromethyl)-5,6-dihyd...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of amino peptidase PMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232524((2R)-4-[8,8-dimethyl-3-(trifluoromethyl)-5,6-dihyd...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50232524((2R)-4-[8,8-dimethyl-3-(trifluoromethyl)-5,6-dihyd...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed