BDBM50234795 CHEMBL4089082

SMILES [H][C@]12NCC[C@@]1(C)c1cc(OC(=O)Nc3ccc(cc3)C(C)C)ccc1N2

InChI Key InChIKey=ZIGIADNCAWZUAB-CTNGQTDRSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50234795   

TargetCholinesterase(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50234795(CHEMBL4089082)
Affinity DataKi:  0.131nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50234795(CHEMBL4089082)
Affinity DataIC50:  1nMAssay Description:Inhibition of human erythrocyte BChE using S-butyrylthiocholine as substrate preincubated for 30 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50234795(CHEMBL4089082)
Affinity DataIC50:  1nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50234795(CHEMBL4089082)
Affinity DataIC50:  110nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50234795(CHEMBL4089082)
Affinity DataIC50:  110nMAssay Description:Inhibition of human plasma AChE using acetyl-(beta-methyl)thiocholine as substrate preincubated for 30 mins followed by substrate addition measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed