BDBM50235643 CHEMBL4076017

SMILES CN(C)[C@H]1CN(C[C@@H]1C1CCN(CC1)c1ccc(cn1)C(N)=O)C1CCc2cccc(F)c12

InChI Key InChIKey=NJCVMTGRSCLQAB-FQXDTITESA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50235643   

TargetPolycomb protein EED(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50235643(CHEMBL4076017)
Affinity DataKi:  0.450nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50235643(CHEMBL4076017)
Affinity DataIC50:  230nMAssay Description:Inhibition of EED in human G401 cells assessed as reduction in H3K27 trymethylation measured after 6 days by alphaLISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50235643(CHEMBL4076017)
Affinity DataIC50:  280nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed