BDBM50236025 CHEMBL2016761::US11149049, No. C2
SMILES Nc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C#N
InChI Key InChIKey=DFVPCNAMNAPBCX-LTGWCKQJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50236025
TargetDNA-directed RNA polymerase, mitochondrial(Homo sapiens (Human))
Gilead Sciences
Curated by ChEMBL
Gilead Sciences
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human mitochondrial RNA polymerase after 30 mins in presence of [33P]GTPMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human DNA polymerase alpha preincubated with enzyme followed by addition of dATP/dGTP/TTP as substrate in presence of [gamm...More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human DNA polymerase beta preincubated with enzyme followed by addition of dATP/dGTP/TTP as substrate in presence of [gamma...More data for this Ligand-Target Pair
TargetRous sarcoma virus integrase(Rous sarcoma virus (strain Prague C) (RSV-PrC))
Janssen Biopharma
US Patent
Janssen Biopharma
US Patent
Affinity DataIC50: 120nMAssay Description:Standard RSV polymerase assays were conducted in the presence of 3 μL extract of RSV-infected cells in a reaction buffer containing 50 mM tris-a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:The enzyme activity of dengue virus NS5 polymerase domain (DENVpol, serotype 2, New Guinea C strain) was measured as an incorporation of tritiated NM...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:The enzyme activity of hepatitis C virus RNA polymerase (HCVpol) and human rhinovirus 16 RNA polymerase (HRV16pol) is measured as an incorporation of...More data for this Ligand-Target Pair