BDBM50236118 CHEMBL4065181

SMILES COc1ccc(cc1OC)-c1nn2c(nnc2s1)-c1cccs1

InChI Key InChIKey=YTGYWPTWNBGCLG-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50236118   

TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50:  20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-ribose pyrophosphatase, mitochondrial(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUridine diphosphate glucose pyrophosphatase NUDT14(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBis(5'-nucleosyl)-tetraphosphatase [asymmetrical](Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50:  20nMAssay Description:Inhibition of human dCTPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human MTH1 using dGTP as substrate after 1 hr by malachite green reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNucleotide triphosphate diphosphatase NUDT15(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human His-tagged NUDT15 expressed in bacterial expression system after 1 hr by malachite green reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine triphosphate pyrophosphatase(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetADP-sugar pyrophosphatase(Homo sapiens (Human))
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human His-tagged NUDT5 expressed in bacterial expression system in presence of ADP after 1 hr by malachite green reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed