BDBM50236118 CHEMBL4065181
SMILES COc1ccc(cc1OC)-c1nn2c(nnc2s1)-c1cccs1
InChI Key InChIKey=YTGYWPTWNBGCLG-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50236118
Affinity DataIC50: 20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
TargetADP-ribose pyrophosphatase, mitochondrial(Homo sapiens (Human))
Karolinska Institutet
Curated by ChEMBL
Karolinska Institutet
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
TargetUridine diphosphate glucose pyrophosphatase NUDT14(Homo sapiens (Human))
Karolinska Institutet
Curated by ChEMBL
Karolinska Institutet
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
TargetBis(5'-nucleosyl)-tetraphosphatase [asymmetrical](Homo sapiens (Human))
Karolinska Institutet
Curated by ChEMBL
Karolinska Institutet
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human dCTPase 1More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Karolinska Institutet
Curated by ChEMBL
Karolinska Institutet
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human MTH1 using dGTP as substrate after 1 hr by malachite green reagent based assayMore data for this Ligand-Target Pair
TargetNucleotide triphosphate diphosphatase NUDT15(Homo sapiens (Human))
Karolinska Institutet
Curated by ChEMBL
Karolinska Institutet
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human His-tagged NUDT15 expressed in bacterial expression system after 1 hr by malachite green reagent based assayMore data for this Ligand-Target Pair
TargetInosine triphosphate pyrophosphatase(Homo sapiens (Human))
Karolinska Institutet
Curated by ChEMBL
Karolinska Institutet
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human His-tagged NUDT5 expressed in bacterial expression system in presence of ADP after 1 hr by malachite green reagent based assayMore data for this Ligand-Target Pair