BDBM50236624 CHEMBL4097420

SMILES [H][C@]12CC[C@]([H])(C1)[C@@H]([C@@H]2NS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO

InChI Key InChIKey=ZUEIUQGEIFOZIJ-GCRLEYHISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50236624   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Mus musculus (Mouse))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50236624(CHEMBL4097420)
Affinity DataIC50:  18nMAssay Description:Inhibition of TACE in mouse RAW264.7 cells assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Mus musculus (Mouse))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50236624(CHEMBL4097420)
Affinity DataIC50:  18nMAssay Description:Inhibition of fibrinogen binding to integrin alphaIIb-beta3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50236624(CHEMBL4097420)
Affinity DataIC50:  0.631nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C delta C1a domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50236624(CHEMBL4097420)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of 0.5 nM [3H]nisoxetine binding to Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed