BDBM50241461 3,7-bis(dimethylamino)phenothiazin-5-ium chloride::Basic Blue 9::CHEMBL405110::Methylenblau::Methylene Blue anhydrous::Methylene blue::Methylene blue (10)::SAMPL5, CBC-G10::azul de metileno::bleu de methylene::cid_6099::methylthioninium chloride
SMILES CN(C)c1ccc2nc3ccc(cc3sc2c1)=[N+](C)C
InChI Key InChIKey=RBTBFTRPCNLSDE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 28 hits for monomerid = 50241461
Affinity DataKi: 110nM ΔG°: -9.49kcal/molepH: 7.0 T: 2°CAssay Description:Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we...More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human full length recombinant tau-441 expressed in Escherichia coli assessed as inhibition of heparin-induced protein aggregation by me...More data for this Ligand-Target Pair
TargetNeutrophil cytosol factor 1 [S99G](Homo sapiens (Human))
Emory University
Curated by PubChem BioAssay
Emory University
Curated by PubChem BioAssay
Affinity DataIC50: 390nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers...More data for this Ligand-Target Pair
TargetCaspase-9(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: 1.70E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
TargetApoptotic protease-activating factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: 1.55E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
TargetApoptotic protease-activating factor 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Burnham Center For Chemical Genomics
Curated by PubChem BioAssay
Affinity DataIC50: >1.00E+5nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...More data for this Ligand-Target Pair
TargetPC4 and SFRS1-interacting protein(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 1.96E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam...More data for this Ligand-Target Pair
TargetFibrinogen beta chain [164-491](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 9.25E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: Harvard Medical School/Massachuset...More data for this Ligand-Target Pair
TargetFibrinogen beta chain [164-491](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 8.33E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: Harvard Medical School/Massachuset...More data for this Ligand-Target Pair
TargetPC4 and SFRS1-interacting protein(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
Affinity DataIC50: 3.65E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: Ohio State University Assay Provider: Mam...More data for this Ligand-Target Pair
TargetIsoform Tau-F of Microtubule-associated protein tau(Homo sapiens (Human))
The Ohio State University
The Ohio State University
Affinity DataIC50: 610nMpH: 7.4Assay Description:The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of His-tagged human brain tau 3R MBD aggregation after 16 hrs by thioflavin T fluorescence methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant MAOA using kynuramine substrate assessed as reduction in MAO-generated 4-hydroxyquinoline level by fluorescence spect...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataIC50: 4.37E+3nMAssay Description:Inhibition of human recombinant MAOB using kynuramine substrate assessed as reduction in MAO-generated 4-hydroxyquinoline level by fluorescence spect...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory concentration against human glutathione reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibitory concentration against Plasmodium falciparum glutathione reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+4nMpH: 6.9Assay Description:Inhibition of human recombinant glutathione reductase at pH 6.9More data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic(Homo sapiens (Human))
Biochemie-Zentrum Der Universit£T Heidelberg
Curated by ChEMBL
Biochemie-Zentrum Der Universit£T Heidelberg
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMpH: 7.4Assay Description:Inhibition of human recombinant TrxR1 at pH 7.4More data for this Ligand-Target Pair
TargetDihydrolipoyl dehydrogenase, mitochondrial(Sus scrofa)
Biochemie-Zentrum Der Universit£T Heidelberg
Curated by ChEMBL
Biochemie-Zentrum Der Universit£T Heidelberg
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMpH: 7.3Assay Description:Inhibition of pig recombinant dihydrolipoamide dehydrogenase at pH 7.3More data for this Ligand-Target Pair
TargetDihydrolipoyl dehydrogenase(Plasmodium falciparum)
Biochemie-Zentrum Der Universit£T Heidelberg
Curated by ChEMBL
Biochemie-Zentrum Der Universit£T Heidelberg
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMpH: 7.3Assay Description:Inhibition of Plasmodium falciparum recombinant dihydrolipoamide dehydrogenase at pH 7.3More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human TAU three-repeat microtubule-binding domain aggregation expressed in Escherichia coli after 16 hrs by thioflavin T fl...More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine preincubated for 5 mins before substrate addition by fluorescence assay in presence of 0.01% Triton X-100More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of Trypanosoma cruzi cruzaine preincubated for 5 mins before substrate addition by fluorescence assay in absence of Triton X-100More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University
Curated by ChEMBL
North-West University
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Inhibition of tau-tau binding (unknown origin) assessed as increase in dissolved paired helical filamentsMore data for this Ligand-Target Pair
Affinity DataEC50: 590nMAssay Description:Inhibition of tau aggregation (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 1.87E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
Affinity DataEC50: 1.14E+5nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 50241461
ITC DataΔG°: -10.3kcal/mole logk: 3.90E+7
pH: 7.4 T: 24.85°C
pH: 7.4 T: 24.85°C