BDBM50242660 CHEMBL4087082
SMILES NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCN(CC2)c2ccccc2)c1
InChI Key InChIKey=IJTBFOMRKCFLIG-KTKRTIGZSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50242660
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Mcdaniel College
Curated by ChEMBL
Mcdaniel College
Curated by ChEMBL
Affinity DataIC50: 891nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 363nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Mcdaniel College
Curated by ChEMBL
Mcdaniel College
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration against radioligand [3H](+)-NAN binding to haloperidol-sensitive sigma binding site in whole guinea pig brainMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Mcdaniel College
Curated by ChEMBL
Mcdaniel College
Curated by ChEMBL
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Mcdaniel College
Curated by ChEMBL
Mcdaniel College
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair