BDBM50242661 CHEMBL4079213

SMILES NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCN(CC2)c2ccccc2F)c1

InChI Key InChIKey=DKPIHFWBNZVINS-HJWRWDBZSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50242661   

TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242661(CHEMBL4079213)
Affinity DataIC50:  407nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242661(CHEMBL4079213)
Affinity DataIC50:  510nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242661(CHEMBL4079213)
Affinity DataIC50:  410nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242661(CHEMBL4079213)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242661(CHEMBL4079213)
Affinity DataIC50:  9.33E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50242661(CHEMBL4079213)
Affinity DataIC50:  501nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed