BDBM50242925 1-{2-(3-Methylpiperazin-1-yl)-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol Dihydrocholoride::CHEMBL469667

SMILES CN1CCN(CC(c2cccc(OC(F)(F)F)c2)C2(O)CCCCC2)CC1

InChI Key InChIKey=AKRIZMRTOCYSRB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242925   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50242925(1-{2-(3-Methylpiperazin-1-yl)-1-[3-(trifluorometho...)
Affinity DataKi:  91nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50242925(1-{2-(3-Methylpiperazin-1-yl)-1-[3-(trifluorometho...)
Affinity DataIC50:  147nMAssay Description:Inhibition of norepinephrine uptake at human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed