BDBM50243501 1-[1-(3-Chlorophenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride::CHEMBL461705

SMILES OC1(CCCCC1)C(CN1CCNCC1)c1cccc(Cl)c1

InChI Key InChIKey=PZQVDLYPNAADGQ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50243501   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243501(1-[1-(3-Chlorophenyl)-2-piperazin-1-ylethyl]cycloh...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]nisoxetine from human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243501(1-[1-(3-Chlorophenyl)-2-piperazin-1-ylethyl]cycloh...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]WIN35428 from human recombinant dopamine transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243501(1-[1-(3-Chlorophenyl)-2-piperazin-1-ylethyl]cycloh...)
Affinity DataIC50:  4.96E+3nMAssay Description:Inhibition of 5HT uptake at human SERT expressed in human JAR cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50243501(1-[1-(3-Chlorophenyl)-2-piperazin-1-ylethyl]cycloh...)
Affinity DataIC50:  38nMAssay Description:Inhibition of norepinephrine uptake at human norepinephrine transporter expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed