BDBM50244625 CHEMBL4076049
SMILES CCCC[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@H](CCN(C\C=C/C[C@@H](NC(=O)[C@@H]2CCCN2C1=O)C(O)=O)S(=O)(=O)c1ccccc1[N+]([O-])=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCC(=O)N1
InChI Key InChIKey=BMHLIYLAFZGSSP-LTHYPCQCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50244625
Affinity DataKi: 0.100nMAssay Description:Displacement of [125I]-[Nle75, Tyr77] Pyr1-apelin-13 from YFP-tagged human APJ receptor expressed in HEK293 cell membranes after 1 hr by gamma-counti...More data for this Ligand-Target Pair
Affinity DataEC50: 1.70nMAssay Description:Activity at human APJ receptor expressed in HEK293 cells assessed as dissociation of Galphai1 from Gbetagamma subunit after 5 mins by BRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 63nMAssay Description:Activity at GFP10-tagged human APJ receptor expressed in HEK293 cells assessed as induction of RlucII-tagged beta-arrestin-2 recruitment after 30 min...More data for this Ligand-Target Pair