BDBM50245860 (R)-4-(3-(2,6-dichlorophenylamino)-6-(phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)butane-1,2-diol::CHEMBL461159

SMILES OC[C@H](O)CCn1nc(Nc2c(Cl)cccc2Cl)c2cnc(Nc3ccccc3)nc12

InChI Key InChIKey=LAOMCQARFXSSHP-CQSZACIVSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245860   

TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245860((R)-4-(3-(2,6-dichlorophenylamino)-6-(phenylamino)...)
Affinity DataKi:  10nMAssay Description:Inhibition of histidine-tagged ACK1 (amino acids 117 to 489) (unknown origin) expressed in SF9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245860((R)-4-(3-(2,6-dichlorophenylamino)-6-(phenylamino)...)
Affinity DataKi:  20nMAssay Description:Inhibition of flag-tagged ACK1 (unknown origin) autophosphorylation expressed in human 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed