BDBM50247358 CHEMBL4071410

SMILES CC1CCC(C)N1C(=O)CNC(=O)Nc1ccc2cnccc2c1

InChI Key InChIKey=BGPQOVRSQPXNFD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50247358   

TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247358(CHEMBL4071410)
Affinity DataIC50:  22nMAssay Description:Inhibition of PRMT3 (unknown origin) using C-terminally biotinylated histone H4 as substrate in presence of [3H]S-adenosylmethionine by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247358(CHEMBL4071410)
Affinity DataIC50:  134nMAssay Description:Inhibition of FLAG-tagged wild type human PRMT3 expressed in HEK293 cells assessed as decrease in exogenous H4R3 dimethylation level using GFP-tagged...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed