BDBM50248657 (E)-2-{3-[(Ethylmethylamino)methyl]benzylidene}-5,6-dimethoxy-2,3-dihydroinden-1-one::CHEMBL463279

SMILES CCN(C)Cc1cccc(\C=C2/Cc3cc(OC)c(OC)cc3C2=O)c1

InChI Key InChIKey=GJSOIUMBSCXVRP-VCHYOVAHSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50248657   

TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50248657((E)-2-{3-[(Ethylmethylamino)methyl]benzylidene}-5,...)
Affinity DataKi:  236nMAssay Description:Binding affinity to acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcetylcholinesterase(Rattus norvegicus (rat))TBA
LigandPNGBDBM50248657((E)-2-{3-[(Ethylmethylamino)methyl]benzylidene}-5,...)
Affinity DataIC50:  487nMAssay Description:Inhibition of acetylcholinesterase in Rattus norvegicus (rat) cortex by Ellman methodMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50248657((E)-2-{3-[(Ethylmethylamino)methyl]benzylidene}-5,...)
Affinity DataIC50:  3.68E+4nMAssay Description:Inhibition of BChE in rat serum after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))TBA
LigandPNGBDBM50248657((E)-2-{3-[(Ethylmethylamino)methyl]benzylidene}-5,...)
Affinity DataIC50:  490nMAssay Description:Inhibition of AChE in rat cortex after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed