BDBM50248793 17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5alpha-epoxy-6beta-(cinnamoylamino)morphinan::CHEMBL473362
SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)[C@@H](CC[C@@]35O)NC(=O)\C=C\c1ccccc1
InChI Key InChIKey=LZOHGRMVIRLGGP-ZHWHHXEDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50248793
Affinity DataKi: 0.0430nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Compound was evaluated for binding affinity against [3H]- DAMGO labeled mu opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cell membrane by liquid scintillation and luminescence counterMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Compound was evaluated for binding affinity against [3H]- U-69593 labeled kappa1 opioid receptor in guinea-pig brain homogenate.More data for this Ligand-Target Pair
Affinity DataKi: 3.10nMAssay Description:Compound was evaluated for binding affinity against [3H]- Cl-DPDPE labeled Opioid receptor delta 1 in guinea-pig brain homogenate.More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in mouse vas deferens(MVD) preparationsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.120nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Compound was evaluated for kappa opioid receptor mediated agonistic effect in electrically stimulated guinea-pig ileumMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cell membrane assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair