BDBM50249131 1-(4'-fluorobiphenyl-4-ylsulfonyl)-4-(1H-imidazol-2-yl)piperidine::CHEMBL472990

SMILES Fc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N1CCC(CC1)c1ncc[nH]1

InChI Key InChIKey=LPLUQDBXZIJXRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50249131   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249131(1-(4'-fluorobiphenyl-4-ylsulfonyl)-4-(1H-imidazol-...)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249131(1-(4'-fluorobiphenyl-4-ylsulfonyl)-4-(1H-imidazol-...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed