BDBM50250068 CHEMBL501240::PACAP(1-27)::PACAP-27::[Glu3]PACAP27

SMILES CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O

InChI Key InChIKey=IAWMQYIXAKXMGI-GIJPRFPSSA-N

Data  7 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50250068   

LigandPNGBDBM50250068(CHEMBL501240 | PACAP(1-27) | PACAP-27 | [Glu3]PACA...)
Affinity DataKi:  0.0800nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVIP peptides(Homo sapiens (Human))
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50250068(CHEMBL501240 | PACAP(1-27) | PACAP-27 | [Glu3]PACA...)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVIP peptides(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50250068(CHEMBL501240 | PACAP(1-27) | PACAP-27 | [Glu3]PACA...)
Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVIP peptides(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50250068(CHEMBL501240 | PACAP(1-27) | PACAP-27 | [Glu3]PACA...)
In DepthDetails ArticlePubMed
TargetVIP peptides(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50250068(CHEMBL501240 | PACAP(1-27) | PACAP-27 | [Glu3]PACA...)
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVIP peptides(RAT)
UniversitÉ

Curated by PDSP Ki Database
LigandPNGBDBM50250068(CHEMBL501240 | PACAP(1-27) | PACAP-27 | [Glu3]PACA...)
In DepthDetails ArticlePubMed
LigandPNGBDBM50250068(CHEMBL501240 | PACAP(1-27) | PACAP-27 | [Glu3]PACA...)
Affinity DataKi:  4.70nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Institut National De La Recherche Scientifique

Curated by ChEMBL
LigandPNGBDBM50250068(CHEMBL501240 | PACAP(1-27) | PACAP-27 | [Glu3]PACA...)
Affinity DataIC50:  10.6nMAssay Description:Displacement of [125I]Ac-PACAP27 from human recombinant PAC1 receptor expressed in CHO cells by gamma- counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPituitary adenylate cyclase-activating polypeptide type I receptor(Homo sapiens (Human))
Institut National De La Recherche Scientifique

Curated by ChEMBL
LigandPNGBDBM50250068(CHEMBL501240 | PACAP(1-27) | PACAP-27 | [Glu3]PACA...)
Affinity DataEC50:  20.6nMAssay Description:Agonist activity at human recombinant PAC1 receptor expressed in CHO cells assessed as PACAP38-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed