BDBM50252391 CHEMBL4080014

SMILES Cc1nc2ccccc2n1Cc1ccc(cc1F)C(=O)NO

InChI Key InChIKey=MULLJXKFRXICHS-UHFFFAOYSA-N

Data  18 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50252391   

TargetHistone deacetylase 1(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  4.32E+3nMAssay Description:Inhibition of human HDAC1 using p53 fluorogenic peptide (379 to 382 residues) RHKKAc as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  500nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  30nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  70nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  2.04E+4nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  4.32E+3nMAssay Description:Inhibition of HADC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  3nMAssay Description:Inhibition of HADC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  8.96E+3nMAssay Description:Inhibition of recombinant full length C-terminal His/FLAG tagged human HDAC1 (1 to 482 residues) expressed in baculovirus infected sf21 insect cells ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  0.810nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using RHK-K(Ac)-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  3nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  3nMAssay Description:Inhibition of human HDAC6 using p53 fluorogenic peptide (379 to 382 residues) RHKKAc as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Ghent University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  2.03E+4nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed