BDBM50253042 CHEMBL4060968

SMILES CC(C)c1cc(n[nH]1)C(=O)N1CCC(C1)NC(=O)C1CC1

InChI Key InChIKey=CXEXTVGTDZRKJS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50253042   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50253042(CHEMBL4060968)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of KDM5A in human PC9 cells assessed as increase in H3K4me3 level after 5 days by mass-spectrometric methodMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50253042(CHEMBL4060968)
Affinity DataIC50:  65nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged KDM5A expressed in baculovirus infected Sf9 insect cells using H3K4me3 peptide as substrate af...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50253042(CHEMBL4060968)
Affinity DataIC50:  65nMAssay Description:Competitive inhibition of carbonic anhydrase-2 in human erythrocyte membranes assessed as reduction in H+ release using CO2 as substrate by Lineweave...More data for this Ligand-Target Pair