BDBM50253043 CHEMBL4071387

SMILES CC(C)c1cc([nH]n1)C(=O)N1CCC(C1)NC(=O)c1ccccc1

InChI Key InChIKey=RNQBSNIBYKAZGI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50253043   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50253043(CHEMBL4071387)
Affinity DataIC50:  99nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged KDM5A expressed in baculovirus infected Sf9 insect cells using H3K4me3 peptide as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50253043(CHEMBL4071387)
Affinity DataEC50:  6.50E+3nMAssay Description:Inhibition of KDM5A in human PC9 cells assessed as increase in H3K4me3 level after 5 days by mass-spectrometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed