BDBM50253797 CHEMBL460366::Ethyl 5-Amino-3-(4-methoxyphenyl)-4-oxo-3,4-dihydrothieno[3,4-d]pyridazine-1-carboxylate::cid_719449

SMILES CCOC(=O)c1nn(-c2ccc(OC)cc2)c(=O)c2c(N)scc12

InChI Key InChIKey=ZHOXCPCRQLGLIL-UHFFFAOYSA-N

Data  3 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50253797   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Vanderbilt Screening Center For Gpcrs, Ion Channels And Transporters

Curated by PubChem BioAssay
LigandPNGBDBM50253797(CHEMBL460366 | Ethyl 5-Amino-3-(4-methoxyphenyl)-4...)
Affinity DataEC50:  0.0145nMAssay Description:Assay Provider: Val Watts Assay Provider Affiliation: Purdue University Grant Title: Allosteric Modulators of D1 Receptors Grant Number: 1 X01 MH0776...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50253797(CHEMBL460366 | Ethyl 5-Amino-3-(4-methoxyphenyl)-4...)
Affinity DataEC50:  1.09E+5nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50253797(CHEMBL460366 | Ethyl 5-Amino-3-(4-methoxyphenyl)-4...)
Affinity DataEC50:  1.59E+3nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetAdenosine receptor A1(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50253797(CHEMBL460366 | Ethyl 5-Amino-3-(4-methoxyphenyl)-4...)
Affinity DataEC50:  4.30E+3nMAssay Description:Modulation of human adenosine A1 receptor expressed in CHO-K1 cells assessed as allosteric effect on [125I]ABA dissociationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50253797(CHEMBL460366 | Ethyl 5-Amino-3-(4-methoxyphenyl)-4...)
Affinity DataIC50:  2.30E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSentrin-specific protease 8(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50253797(CHEMBL460366 | Ethyl 5-Amino-3-(4-methoxyphenyl)-4...)
Affinity DataIC50:  5.63E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSentrin-specific protease 8(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50253797(CHEMBL460366 | Ethyl 5-Amino-3-(4-methoxyphenyl)-4...)
Affinity DataIC50:  5.63E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay