BDBM50255681 CHEMBL473448::N-[1-(2S-Ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-4-(4-methyl-pyridine-3-sulfonylamino)-benzamide

SMILES CC[C@@H]1OCC(=O)[C@H]1NC(=O)[C@H](CC1(C)CCCC1)NC(=O)c1ccc(NS(=O)(=O)c2cnccc2C)cc1

InChI Key InChIKey=DCDFVKDUIGKXRF-UMXIMWEHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50255681   

TargetCathepsin S(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50255681(CHEMBL473448 | N-[1-(2S-Ethyl-4-oxo-tetrahydro-fur...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of human recombinant cathepsin S expressed in baculovirus by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50255681(CHEMBL473448 | N-[1-(2S-Ethyl-4-oxo-tetrahydro-fur...)
Affinity DataKi:  260nMAssay Description:Inhibition of human recombinant cathepsin K expressed in baculovirus by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Medivir

Curated by ChEMBL
LigandPNGBDBM50255681(CHEMBL473448 | N-[1-(2S-Ethyl-4-oxo-tetrahydro-fur...)
Affinity DataKi:  8.70E+3nMAssay Description:Inhibition of human cathepsin L by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed