BDBM50255898 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1-methyl-3-piperidinyl]-1H-benzimidazole::CHEMBL518950

SMILES CN1CCC[C@H](C1)c1nc2ccccc2n1C1CCN(CC1)C1(C)CCCCCCC1

InChI Key InChIKey=POYRSGAKCBVQQE-JOCHJYFZSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50255898   

TargetNociceptin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]enadoline from human kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataKi: >500nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataEC50:  2.19E+3nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed