BDBM50256887 (S)-ethyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(sulfamoylamino)hexan-2-ylcarbamate::CHEMBL515411

SMILES CCOC(=O)N[C@@H](CCCCNS(N)(=O)=O)C(=O)Nc1nc(cs1)-c1ccccc1

InChI Key InChIKey=CRZWRKQPQRSBOI-AWEZNQCLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50256887   

TargetHistone deacetylase 6(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50256887((S)-ethyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(s...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant His-tagged HDAC6 expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50256887((S)-ethyl 1-oxo-1-(4-phenylthiazol-2-ylamino)-6-(s...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC1 expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed