BDBM50258083 CHEMBL494183::N-(2-(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-4-methylbenzamide::cid_21429000

SMILES Cc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O

InChI Key InChIKey=IISXBFMJBUQZEA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50258083   

TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50258083(CHEMBL494183 | N-(2-(4-(5-chloro-2-oxo-2,3-dihydro...)
Affinity DataIC50:  240nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258083(CHEMBL494183 | N-(2-(4-(5-chloro-2-oxo-2,3-dihydro...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human PLD1 in Calu1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt Specialized Chemistry Center

Curated by PubChem BioAssay
LigandPNGBDBM50258083(CHEMBL494183 | N-(2-(4-(5-chloro-2-oxo-2,3-dihydro...)
Affinity DataIC50:  240nMAssay Description:Inhibition of GFP-labelled human PLD2 HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258083(CHEMBL494183 | N-(2-(4-(5-chloro-2-oxo-2,3-dihydro...)
Affinity DataIC50:  9nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay