BDBM50260025 CHEMBL4087485

SMILES CC1CN(Cc2cc(ccc12)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C(F)(F)F)c1cncnc1

InChI Key InChIKey=YXESXLYKZKCWFJ-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50260025   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50260025(CHEMBL4087485)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human His-tagged c-kit cytoplasmic domain (544 to 976 residues) expressed in baculovirus expression system using Ser/Thr 6 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDiscoidin domain-containing receptor 2(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50260025(CHEMBL4087485)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of recombinant human GST-tagged DDR2 cytoplasmic domain expressed in baculovirus expression system using Fluorescein-Poly GAT as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50260025(CHEMBL4087485)
Affinity DataIC50:  21nMAssay Description:Inhibition of human GST-tagged DDR1 (440 to 876 residues) expressed in baculovirus expression system using fluorescein-Poly GAT as substrate incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50260025(CHEMBL4087485)
Affinity DataIC50:  2.10E+3nMAssay Description:Binding affinity for cannabinoid receptor 2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Jinan University

Curated by ChEMBL
LigandPNGBDBM50260025(CHEMBL4087485)
Affinity DataIC50:  38nMAssay Description:Inhibition of recombinant human GST-tagged DDR1 catalytic domain expressed in baculovirus expression system using Fluorescein-Poly GAT as substrate m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB