BDBM50260939 3-(3-Chloro-3'-methanesulfonyl-biphenyl-4-yl)-5-[1-(4-chloro-phenyl)-cyclobutyl]-4-methyl-4H-[1,2,4]triazole::CHEMBL495889

SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccc(cc1Cl)-c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=WMIKNIOIIKGHNU-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50260939   

TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260939(3-(3-Chloro-3'-methanesulfonyl-biphenyl-4-yl)-5-[1...)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human PXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260939(3-(3-Chloro-3'-methanesulfonyl-biphenyl-4-yl)-5-[1...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human 11beta HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260939(3-(3-Chloro-3'-methanesulfonyl-biphenyl-4-yl)-5-[1...)
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse 11beta HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260939(3-(3-Chloro-3'-methanesulfonyl-biphenyl-4-yl)-5-[1...)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of mouse 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50260939(3-(3-Chloro-3'-methanesulfonyl-biphenyl-4-yl)-5-[1...)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of human 11beta HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed