BDBM50261126 CHEMBL497749::N-(3-(4-(2-methoxyphenyl)piperazin-1-yl)propyl)naphthalene-2-sulfonamide::Naphthalene-2-sulfonic acid {3-[4-(2-methoxyphenyl)-piperazin-1-yl]-propyl}-amide

SMILES COc1ccccc1N1CCN(CCCNS(=O)(=O)c2ccc3ccccc3c2)CC1

InChI Key InChIKey=YRVKJIDCHIEELY-UHFFFAOYSA-N

Data  7 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50261126   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  4.60nMAssay Description:Binding affinity to 5HT1A receptor in rat hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  4.64nMAssay Description:Displacement of [3H]MK912 from human alpha2A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  20nMAssay Description:Binding affinity to human cloned 5HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  85nMAssay Description:Binding affinity to 5HT2A receptor in rat cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  112nMAssay Description:Displacement of [3H]8OH-DPAT from human 5HT1A receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataKi:  132nMAssay Description:Displacement of [3H]spiperone from human D2L receptor after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataIC50:  241nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataIC50:  85nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of LièGe

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataIC50:  4.60nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataIC50:  20nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50261126(CHEMBL497749 | N-(3-(4-(2-methoxyphenyl)piperazin-...)
Affinity DataIC50:  2.63E+3nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed