BDBM50265869 3-(2-(1-(2-(dimethylamino)acetyl)-5-methoxyindolin-6-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)thiophene-2-carboxamide::CHEMBL514873

SMILES COc1cc2CCN(C(=O)CN(C)C)c2cc1Nc1nc(Nc2ccsc2C(N)=O)c2cc[nH]c2n1

InChI Key InChIKey=FLTJPMCKNUNPRH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50265869   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265869(3-(2-(1-(2-(dimethylamino)acetyl)-5-methoxyindolin...)
Affinity DataIC50:  10nMAssay Description:Inhibition of IGF1R phosphorylation by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265869(3-(2-(1-(2-(dimethylamino)acetyl)-5-methoxyindolin...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265869(3-(2-(1-(2-(dimethylamino)acetyl)-5-methoxyindolin...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50265869(3-(2-(1-(2-(dimethylamino)acetyl)-5-methoxyindolin...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of IRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed