BDBM50266967 CHEBI:66678::CHEMBL3393621

SMILES Oc1ccccc1C(=O)c1[nH]c(Cl)c(Cl)c1-n1c(Cl)c(Cl)cc1C(=O)c1ccccc1O

InChI Key InChIKey=QYPJBTMRYKRTFG-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50266967   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50266967(CHEBI:66678 | CHEMBL3393621)
Affinity DataKi:  10nMAssay Description:Inhibition of MCl-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Hunan Provinc

Curated by ChEMBL
LigandPNGBDBM50266967(CHEBI:66678 | CHEMBL3393621)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of biotin labelled Bid-BH3 binding to C-terminal GST-tagged human BCL-XL transmembrane domain expressed in Escherichia coli BL21 (DE3) pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Hunan Provinc

Curated by ChEMBL
LigandPNGBDBM50266967(CHEBI:66678 | CHEMBL3393621)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of biotinylated Bim BH3 peptide binding to GST-tagged human Bcl-xl expressed in Escherichia coli BL21 (DE3) incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50266967(CHEBI:66678 | CHEMBL3393621)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of biotinylated Bim BH3 peptide binding to GST-tagged mouse MCL1 expressed in Escherichia coli BL21 (DE3) incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50266967(CHEBI:66678 | CHEMBL3393621)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of biotinylated Bim BH3 peptide binding to GST-tagged mouse Mcl-1 expressed in Escherichia coli BL21 (DE3) pre-incubated for 1 hr followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50266967(CHEBI:66678 | CHEMBL3393621)
Affinity DataIC50:  1.01E+4nMAssay Description:In vitro inhibitory activity against monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed