BDBM50271166 CHEMBL4130055
SMILES [H][C@@]12CCC[C@@]1(NC(=N)N(C)S2(=O)=O)c1cc(NC(=O)c2ccc(OC(F)F)cn2)ccc1F
InChI Key InChIKey=KUEMKDZBSBUMIV-OXQOHEQNSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50271166
Affinity DataKi: 4nMAssay Description:Binding affinity to human BACE1 catalytic domain using QSY7-APPswe-Eu as substrate preincubated for 30 mins followed by substrate addition measured a...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Binding affinity to human autoBACE2 using QSY7-APPswe-Eu as substrate preincubated for 30 mins followed by substrate addition measured after 90 mins ...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:The compounds of the invention were assessed for their ability to inhibit BACE-1 using the following assay. The resulting values are reported in the ...More data for this Ligand-Target Pair