BDBM50274998 CHEMBL4126811

SMILES CC(C)(C)OC(=O)Nc1ccc(cc1)-c1cc(no1)C(=O)NCc1ccc(cc1)C(=O)NO

InChI Key InChIKey=XHXYWMSIIVJNOP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50274998   

TargetHistone deacetylase 6(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50274998(CHEMBL4126811)
Affinity DataIC50: <10nMAssay Description:Inhibition of recombinant human full length HDAC6 expressed in baculovirus infected Sf9 insect cells using RHKKAC as substrate incubated for 5 to 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50274998(CHEMBL4126811)
Affinity DataIC50:  0.330nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in baculovirus infected sf9 insect cells using p53 (379 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50274998(CHEMBL4126811)
Affinity DataIC50:  436nMAssay Description:Inhibition of recombinant full length C-terminal His/FLAG tagged human HDAC1 (1 to 482 residues) expressed in baculovirus infected sf9 insect cells u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed