BDBM50279601 CHEMBL4161551
SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc4CCN(C(=O)Cn5cccn5)c4c3)c3ccccc3)C(=O)Nc2c1
InChI Key InChIKey=HEKLHRGCBLROOS-DQSJHHFOSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50279601
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: >30nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant VEGFR2 (unknown origin) by off-chip mobility shift assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Mus musculus (mouse))
Shenyang Pharmaceutical University
Curated by ChEMBL
Shenyang Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 9...More data for this Ligand-Target Pair