BDBM50287321 CHEMBL434401::{3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-isopropyl-1H-indol-2-yl]-2,2-dimethyl-propyl}-urea
SMILES CC(C)c1ccc2n(Cc3ccc(Cl)cc3)c(CC(C)(C)CNC(N)=O)c(SC(C)(C)C)c2c1
InChI Key InChIKey=DOOBSCQSXIPWRS-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50287321
TargetArachidonate 5-lipoxygenase-activating protein/Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 970nMAssay Description:Human whole blood was stimulated with calcium ionophore (A23187) and LTB 4 measured by enzyme immunoassayMore data for this Ligand-Target Pair
TargetArachidonate 5-lipoxygenase-activating protein/Polyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophilsMore data for this Ligand-Target Pair