BDBM50290705 (3-{2-[4-(1H-Benzoimidazole-2-carbonyl)-piperidin-1-yl]-ethyl}-3-phenyl-pyrrolidin-1-yl)-(3,4,5-trimethoxy-phenyl)-methanone::CHEMBL330499

SMILES COc1cc(cc(OC)c1OC)C(=O)N1CCC(CCN2CCC(CC2)C(=O)c2nc3ccccc3[nH]2)(C1)c1ccccc1

InChI Key InChIKey=XHIAYAAKBSHSOX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50290705   

TargetSubstance-P receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50290705((3-{2-[4-(1H-Benzoimidazole-2-carbonyl)-piperidin-...)
Affinity DataIC50:  36nMAssay Description:Antagonism of the guinea pig tachykinin NK1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetHistamine H1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290705((3-{2-[4-(1H-Benzoimidazole-2-carbonyl)-piperidin-...)
Affinity DataIC50:  500nMAssay Description:Antagonism of the human histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetHistamine H1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290705((3-{2-[4-(1H-Benzoimidazole-2-carbonyl)-piperidin-...)
Affinity DataIC50:  6.30nMAssay Description:Antagonistic activity against histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(GUINEA PIG)
TBA

Curated by ChEMBL
LigandPNGBDBM50290705((3-{2-[4-(1H-Benzoimidazole-2-carbonyl)-piperidin-...)
Affinity DataIC50:  7.40nMAssay Description:Antagonistic activity against Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails Article