BDBM50291795 CHEMBL441503::{3-[3-(4,6-Diamino-2,2-dimethyl-2H-[1,3,5]triazin-1-yl)-benzyloxy]-phenyl}-methanol

SMILES CC1(C)N=C(N)N=C(N)N1c1cccc(COc2cccc(CO)c2)c1

InChI Key InChIKey=XHJNBBKNRVVKOH-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50291795   

TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50291795(CHEMBL441503 | {3-[3-(4,6-Diamino-2,2-dimethyl-2H-...)
Affinity DataKi:  5.5nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50291795(CHEMBL441503 | {3-[3-(4,6-Diamino-2,2-dimethyl-2H-...)
Affinity DataKi:  25.1nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50291795(CHEMBL441503 | {3-[3-(4,6-Diamino-2,2-dimethyl-2H-...)
Affinity DataKi:  79nMAssay Description:Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50291795(CHEMBL441503 | {3-[3-(4,6-Diamino-2,2-dimethyl-2H-...)
Affinity DataKi:  646nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from Leishmania majorChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase type 1(Escherichia coli)
TBA

Curated by ChEMBL
LigandPNGBDBM50291795(CHEMBL441503 | {3-[3-(4,6-Diamino-2,2-dimethyl-2H-...)
Affinity DataKi:  646nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed